Students will gain a thorough understanding of hazard assessment with a focus on metals in toxicology. This course unit integrates principles of toxicology, the role of metals in toxicity and health, and advanced methods for studying chemical interactions with DNA, providing view of the molecular and systemic effects of metal exposure.The student is expected to be able to:1. Identify toxic metals, their sources of exposure, and their health effects, and understand the molecular mechanisms of metal toxicity, including their potential applications in therapeutic metallodrugs;2. Analyze and apply methods to study chemical interactions with DNA, including techniques such as voltammetry, Surface Plasmon Resonance (SPR), and switchSense, with an emphasis on evaluating DNA-metal interactions;3. Apply the principles of toxicology and ecotoxicology to assess the risks posed by metals in environmental and occupational settings, understanding their role in dose-response relationships and systemic toxicity.